-2%
Freegest is prescribed for the following conditions:
- Prophylaxis and long-term management of asthma.
- Prevention of Exercise-Induced Bronchoconstriction (EIB).
- Relief of symptoms associated with Allergic Rhinitis (AR), including both seasonal and perennial forms.
Montelukast is a selective, orally active leukotriene receptor antagonist that blocks the cysteinyl leukotriene receptor (CysLT₁). The cysteinyl leukotrienes (LTC₄, LTD₄, and LTE₄) are inflammatory mediators derived from arachidonic acid and released by mast cells and eosinophils. These compounds contribute to airway inflammation, edema, smooth muscle contraction, and tissue remodeling seen in asthma and allergic rhinitis. By inhibiting CysLT₁ receptors, Montelukast reduces airway inflammation and relieves allergic symptoms.