-5%
Vilanterol is a long-acting beta-2 agonist (LABA) that relaxes airway smooth muscle and reduces bronchospasm by increasing cyclic AMP.
Fluticasone Furoate is an inhaled corticosteroid (ICS) that reduces airway inflammation by acting on multiple immune cells and inflammatory mediators.
Umeclidinium is a long-acting muscarinic antagonist (LAMA) that blocks M3 receptors in airway smooth muscle, causing bronchodilation.
Vilanterol Trifenatate + Fluticasone Furoate + Umeclidinium Bromide
- COPD (Chronic Obstructive Pulmonary Disease): For long-term maintenance in adult patients.
- Asthma: For maintenance treatment in adults (18 years and older).
- Limitation of use: Not intended for the relief of acute bronchospasm.
- Children & adolescents (<18 years): Not recommended
- Elderly: No dosage adjustment required, though sensitivity may vary
- Renal/Hepatic impairment: Not studied