-5%
Pegfilgrastim, the active ingredient in PegNeufil, is a pegylated Granulocyte Colony-Stimulating Factor (G-CSF). It stimulates the production and release of functional neutrophils from the bone marrow. Pegfilgrastim is a covalent conjugate of recombinant human G-CSF (Filgrastim) and polyethylene glycol. It has a molecular weight of approximately 39 kD. The pegylation increases its half-life and efficacy, making it suitable for single-dose administration per chemotherapy cycle.
PegNeufil is a leukocyte growth factor used to reduce the risk of infection, as indicated by febrile neutropenia, in patients with non-myeloid malignancies undergoing myelosuppressive chemotherapy associated with a significant risk of febrile neutropenia.
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