-5%
Tablet Manufacturer/Distributor: Aristopharma Limited Generic Name: Bisoprolol Hemifumarate 10 mg + Hydrochlorothiazide 6.25 mg Tablet
Indications of Ancor 10 Tablet
Bisoprolol is indicatedin-
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology of Ancor 10 Tablet
Bisoprolol Fumarate is the most selective ß1 blocker. It has the highest affinity for ß1 receptors compared to any other beta-blocker available to date. It selectively blocks ß1 adrenergic receptors in the heart and vascular smooth muscle, reduces heart rate and cardiac output, thereby reducing arterial hypertension. In patients using non-selective β1-blockers for β1, β-blockers may adversely affect lipid metabolism, but in long-term treatment, bisoprolol does not cause HDL, including cardioprotective effects. Any change in the components of cholesterol, including cholesterol.
Dosage & Administration of Ancor 10 Tablet
Hypertension: The dose of Bisoprolol must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily.
Angina: Usually 10 mg once daily (5 mg may be adequate in some patients) max 20 mg daily.
Heart Failure: Initially 1.25 mg once daily (in the morning) for 1 week then, if well tolerated, increased to 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then- 7.5 mg once daily for 4 weeks, then 10 mg once daily maximum 10 mg daily.
Interaction of Ancor 10 Tablet
Bisoprolol should not be combined with other beta blockers.
Contraindications
Patients with cardiogenic shock, obvious heart failure, second or third degree atrioventricular block, right ventricular failure secondary to pulmonary hypertension, and sinus bradycardia.
Side Effects of Ancor 10 Tablet
There may be gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbance, dizziness, dizziness, thrombocytopenia, visual disturbance, and hair loss.
Pregnancy & Lactation
The safety of bisoprolol during pregnancy has not been established. There are no data on breastfeeding.
Precautions & Warnings
Kidney monitoring, liver and hematopoietic function must be carried out regularly during long-term treatment with bisoprolol.
Storage Conditions
Store in a cool & dry place and away from children.