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Neumir 5 | 1 Strip

SKU: 144270

Manufacturer: Navana Pharmacuticals Ltd.

Generic: Mirogabalin Besylate

Type: Tablet

Pack Size: 10 Pcs

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Description

Mirogabalin, a γ-aminobutyric acid derivative, selectively binds to α2δ subunits of voltage-gated calcium channels (VGCCs). This reduces calcium influx at nerve endings, limiting neurotransmitter release and decreasing neuronal hyperexcitability.

  • Absorption: Rapid (Tmax 0.5–1.5h)
  • Protein binding: ~25%
  • Distribution volume: 64–88L
  • Metabolism: Minimal hepatic metabolism (UGT pathway)
  • Excretion: 99% renal (mostly unchanged)
  • Half-life: 2–4.9h

Migalin (Mirogabalin) Tablet

  • Neuropathic Pain
  • Diabetic Peripheral Neuropathic Pain (DPNP)
  • Postherpetic Neuralgia (PHN)
  • Peripheral Neuropathic Pain (PNP)