-5%
- Apuldon 10 helps relieve nausea, vomiting, and indigestion.
- Apuldon 10 should be taken before meals as per the dose and duration prescribed by your doctor.
- Apuldon 10 Tablet may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Avoid consuming alcohol when taking Apuldon 10 Tablet, as it may cause excessive drowsiness.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help.
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
- Do not take Apuldon Tablet for longer than 7 days without consulting your doctor.
- Take 15–30 minutes before meals and, if needed, before bedtime.
Domperidone blocks dopamine receptors located in the chemoreceptor trigger zone (CTZ) and within the stomach. By antagonizing dopamine’s inhibitory effect on gut motility, it normalizes upper GI tone and movement, speeds gastric emptying, enhances antral/duodenal peristalsis, and coordinates pyloric contractions. It also increases esophageal peristalsis and raises lower esophageal sphincter pressure, reducing reflux. Because it crosses the blood–brain barrier poorly, psychotropic and neurologic effects are uncommon.
Overdose
Symptoms: drowsiness, disorientation, extrapyramidal reactions (especially in children).
Management: administer activated charcoal, observe closely. For EPS, consider anticholinergic antiparkinson agents or antihistamines with anticholinergic properties.