Atrogen 1% Eye Drops 10ml
Atrogen 1% Eye Drops 10ml Original price was: 70.21৳ .Current price is: 66.70৳ .
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Audicom 0.3%+1%+0.025%+2% Ear Drop 10ml
Audicom 0.3%+1%+0.025%+2% Ear Drop 10ml Original price was: 150.00৳ .Current price is: 147.00৳ .
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Audicare Ear Drops 10ml

SKU: 143238

Manufacturer: Aristopharma Limited

Generic: Ofloxacin + Clotrimazole + Beclomethasone + Lidocaine

Type: Drops

Pack Size: 10ml

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Original price was: 150.00৳ .Current price is: 142.50৳ .

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Description

Ofloxacin 0.3% + Clotrimazole 1% + Beclomethasone 0.025%+ Lidocaine 2% is used in the treatment of ear infection.

Antibacterial: Ofloxacin

  • Mechanism of Action: Inhibits DNA gyrase of bacteria, exerting broad-spectrum antibacterial activity.
  • Activity Against: Gram-positive bacteria (Staphylococcus aureus, Streptococcus pneumoniae) and Gram-negative bacteria (Escherichia coli, Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, Pseudomonas aeruginosa).
  • Clinical Advantage: Effective against otic pathogens without ototoxicity, making it preferable over Aminoglycosides for middle ear infections.

Antifungal: Clotrimazole

  • Mechanism of Action: Inhibits Cytochrome P-450 synthesis of Ergosterol, reducing fungal cell wall integrity and inhibiting fungal growth.
  • Activity Against: Fungi responsible for superficial mycotic infections, including Candida, Microsporum, and Trichophyton.
  • Clinical Advantage: Offers broad-spectrum antifungal activity and also exhibits antibacterial effects against certain bacteria like Streptococci and Staphylococci, beneficial for mixed bacterial-fungal infections.

Anti-inflammatory: Beclomethasone Dipropionate

  • Mechanism of Action: Potent steroid with anti-inflammatory, antipruritic, and vasoconstrictive properties.
  • Activity: Induces phospholipase A2 inhibition, leading to suppression of inflammatory mediators such as prostaglandins and leukotrienes.
  • Clinical Advantage: Provides relief from inflammation associated with otic infections, reducing symptoms like pain and swelling.

Topical Local Anesthetic: Lidocaine Hydrochloride

  • Mechanism of Action: Blocks sodium channels, preventing nerve signal transmission and providing local anesthesia.
  • Clinical Advantage: Alleviates pain and stinging sensation in the ear, improving patient comfort during treatment.

Formulation and Functionality:

  • Designed to maintain the natural environment of the external ear canal.
  • Combines antibacterial, antifungal, anti-inflammatory, and local anesthetic agents for effective management of otic infections.
  • Each component targets specific aspects of infection, ensuring comprehensive treatment and symptom relief.