Folita 5mg Tablet
Folita 5mg Tablet Original price was: 90.00৳ .Current price is: 85.50৳ .
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Foly 15 Tablet 14pcs
Foly 15 Tablet 14pcs Original price was: 350.00৳ .Current price is: 332.50৳ .
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Folix 5mg Tablet 1 Strip

SKU: 140770

Manufacturer: Acme Laboratories Ltd.

Generic: Folinic Acid

Type: Tablet

Pack Size: 10 Pcs

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Original price was: 90.00৳ .Current price is: 85.50৳ .

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Description

Calcium Folinate Hydrate (Folinic Acid): Active metabolite of folic acid.

Each tablet contains:

  • Calcium Folinate Hydrate BP 6.249 mg (Equivalent to Folinic Acid 5 mg).
  • Calcium Folinate Hydrate BP 18.746 mg (Equivalent to Folinic Acid 15 mg).

Folinic Acid is a calcium salt of tetrahydrofolic acid (a metabolite of folic acid). It is a cofactor in purine and pyrimidine biosynthesis, essential for DNA and RNA synthesis. Acts as an antidote to folic acid antagonists (e.g., methotrexate) by “rescuing” normal cells from toxicity. Folinic acid does not interfere with the antibacterial activity of folate antagonists like trimethoprim.

Folinic Acid/Folix is indicated for:

Neutralizing Toxic Effects of Folic Acid Antagonists:

  • E.g., Methotrexate, Pyrimethamine, Trimethoprim.

Calcium Folinate Rescue Therapy:

  • Administered alongside high-dose Methotrexate to minimize systemic toxicity.

Treatment of Megaloblastic Anemia:

  • Caused by folate deficiency due to conditions like:
    • Sprue.
    • Nutritional deficiency.
    • Pregnancy.
    • Infancy.
    • Liver disease.
    • Malabsorption syndrome.