Moxibac XG Eye Drops

Indications of Moxibac XG Eye Drops

Moxibac XG is used to treat bacterial conjunctivitis caused by the susceptible strains of the following organisms:

Aerobic Gram-positive microorganisms include Corynebacterium species, Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Streptococcus pneumoniae, and the Streptococcus viridans group.
Acinetobacter iwoffii, Haemophilus influenzae, and Haemophilus parainfluenzae are examples of Gram-negative aerobic microorganisms.

Pharmacology

Moxifloxacin is a 4th generation synthetic broad-spectrum antibacterial drug that belongs to the fluoroquinolone class of antibiotics. It is effective against a wide variety of bacteria, including gram-positive, gram-negative, anaerobic, and atypical Mycoplasma pneumonia. Topoisomerase II (DNA gyrase) and topoisomerase IV are inhibited, which are required for bacterial DNA replication, transcription, and repair.

Administration & Dosage of Moxibac XG Eye Drops

• Instill 1 drop in the affected eye(s) 2 times daily for 7 days.

Interaction

Moxifloxacin absorption is reduced when antacids, sucralfate, multivitamins, and multivalent cations are combined (e.g. iron or zinc). Moxifloxacin may increase the risk of convulsions and bleeding when combined with NSAIDs and warfarin. As a result, using Moxifloxacin alongside them should be avoided.

Contraindications

Moxibac XG ophthalmic solution is contraindicated in patients with a history of hypersensitivity to moxifloxacin, to other quinolones, or to any of the components in this medication.

Side Effect

• Nausea
• Vomiting 
• Diarrhea
• Headaches 
• Dizziness

Precautions & Warnings

Tendinitis and tendon rupture are possible side effects of moxifloxacin. If a tendon becomes inflamed or painful, it should be stopped. It should not be used in patients who have a known prolongation of the QT interval, hypokalemia that has not been corrected, or who are taking Class IA or Class III antiarrhythmics.

• Even if you feel better, do not skip any doses and complete the entire course of treatment.
• Immediately after instilling the medication, apply pressure to the corner of the eye (close to the nose) for about 1 minute.
• To avoid contamination, avoid touching the tip to any surface or your eye.
• To avoid dilution, wait at least 5-10 minutes before administering the next medication in the same eye.
• When first used, it may cause temporary blurring of vision. Use caution when driving or operating machinery.
• Wearing contact lenses is not recommended until your infection has cleared up.
• Use the medication within 4 weeks of opening it.

Pregnancy & Lactation

Pregnancy category C according to the US Food and Drug Administration. During pregnancy and lactation, moxifloxacin is not recommended.

Storage Conditions

Store at room temperature and protect from light and moisture. It is desirable that the contents should not be used more than one month after the first opening of the bottle.