-2%
Pantoprazole is used for the management of various acid-related gastrointestinal conditions, including:
- Peptic ulcer disease (duodenal and gastric ulcers)
- H. pylori infection (as part of combination therapy)
- Gastroesophageal reflux disease (GERD) with or without erosive esophagitis
- Zollinger-Ellison syndrome
- Oesophagitis
- Acid-related dyspepsia
- NSAID-associated ulceration
- Ulcers resistant to H2 receptor antagonists
- Stress-related GI bleeding
- Prophylaxis for acid aspiration during anesthesia
Pantoprazole is a substituted benzimidazole that inhibits the H+/K+ ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion. It suppresses both basal and stimulated gastric acid production.
