-5%
Sezol DS is indicated in the treatment of:
Intestinal Amoebiasis
Hepatic Amoebiasis (with drainage of pus in suppurative stage if needed)
Urethritis & Vaginitis caused by Trichomonas vaginalis
Giardiasis
Secnidazole, a second-generation 5-nitroimidazole derivative, is rapidly absorbed after oral administration. Following a 2 g oral dose, peak plasma concentration is achieved within 3 hours. It has a long elimination half-life of ~20 hours, ensuring therapeutic serum levels for up to 72 hours from a single dose. Around 50% of the ingested dose is excreted in urine within 120 hours. Its long half-life provides sustained antiprotozoal activity.