-5%
Acitretin is a retinoid, similar to Vitamin A. Its exact mechanism is not fully understood, but it is known to:
- Modulate cellular differentiation in the epidermis
- Regulate RNA/DNA synthesis
- Influence epidermal proliferation
- Modify glycoprotein synthesis and immune response
The result is more normal skin cell growth, improving thickened, scaly, and inflamed skin.
Soritec contains Acitretin, an oral retinoid (Vitamin A analogue) used to treat severe skin conditions that do not respond to other therapies.
Adults & Elderly:
- Initial dose: 25–30 mg daily for 2–4 weeks
- Maintenance: 25–50 mg daily for 6–8 weeks for optimal results
- Maximum dose: 75 mg/day in some cases
Darier’s disease:
- Start at 10 mg/day and increase cautiously
Congenital ichthyosis & Darier’s disease:
- Therapy may continue beyond 3 months; use the lowest effective dose (≤50 mg/day)
- Continuous use beyond 6 months is not recommended
Children:
Typical dose: 0.5 mg/kg daily
Can increase up to 1 mg/kg daily, max 35 mg/day for short periods
Always follow your doctor’s instructions carefully.
