-2%
Sucralfate exhibits a local effect in the gastrointestinal tract as it is minimally absorbed systemically. Once administered, it binds to ulcerated areas, forming a viscous, protective barrier. This protective layer shields the ulcer site from pepsin, gastric acid, and bile, facilitating healing. The small amount absorbed is primarily excreted through the urine.
- Children (<14 years): Not recommended due to lack of safety data.
- Elderly: No specific dosage adjustment required.
- Renal Dysfunction: Use with caution; monitor for aluminum toxicity.
- Driving/Operating Machinery: Avoid if dizziness or drowsiness occurs.
Ulfix 1000 is prescribed for individuals aged 14 years and older in the management of:
- Duodenal ulcers
- Gastric ulcers
- Chronic gastritis
- Prevention of gastrointestinal bleeding associated with stress ulcers in critically ill patients