-5%
Montelukast is a selective, orally active leukotriene receptor antagonist that blocks the cysteinyl leukotriene receptor (CysLT1). Cysteinyl leukotrienes (LTC4, LTD4, LTE4), products of arachidonic acid metabolism, are released by cells such as mast cells and eosinophils. These leukotrienes are involved in the pathophysiology of asthma and allergic rhinitis, contributing to airway swelling, smooth muscle contraction, and other inflammatory processes that lead to asthma symptoms.
